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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBL1XR1 All Species: 43.64
Human Site: S186 Identified Species: 64
UniProt: Q9BZK7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZK7 NP_078941.2 514 55595 S186 P V S D L L A S G S G D S T A
Chimpanzee Pan troglodytes XP_521379 534 57733 S196 P V S D L L A S G S G D S T A
Rhesus Macaque Macaca mulatta XP_001101823 506 54482 S178 P V S D L L A S G S G D S T A
Dog Lupus familis XP_850905 514 55709 S186 P V S D L L A S G S G D S T A
Cat Felis silvestris
Mouse Mus musculus Q8BHJ5 514 55642 S186 P V S D L L A S G S G D S T A
Rat Rattus norvegicus Q5M7T1 339 37599 T29 L A W N P T G T L L A S C G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516513 527 56747 S199 P V S D L L A S G S G D S T A
Chicken Gallus gallus NP_001153226 523 56567 S195 P V S D L L A S G S G D S T A
Frog Xenopus laevis Q6GPC6 522 56266 S194 P V S D L L A S G S G D S T A
Zebra Danio Brachydanio rerio Q803D2 410 46511 E100 E W I P R P P E K Y A L S G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95RJ9 700 72369 S372 P S R D L L A S G S G D S T A
Honey Bee Apis mellifera XP_393667 512 56104 S184 P T T D L L A S G S G D S T A
Nematode Worm Caenorhab. elegans Q17963 376 40375 A66 A Q T P N P N A A G A S A S G
Sea Urchin Strong. purpuratus XP_001198347 493 53832 S172 R D L L A S G S G D S T A R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLX9 473 52879 G163 T V A W S P D G K H L V S G S
Baker's Yeast Sacchar. cerevisiae P38262 535 59143 Y175 L D E S I L A Y G E K N S V A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 96.8 99 N.A. 99 21 N.A. 88.8 90.2 96.7 22.1 N.A. 55.7 74.1 21.7 79.3
Protein Similarity: 100 89.1 97.4 99.4 N.A. 99.2 32.2 N.A. 93.5 94.8 97.3 38.5 N.A. 64.5 81.5 36.7 85.8
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 100 100 100 6.6 N.A. 86.6 86.6 0 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 100 100 6.6 N.A. 86.6 93.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 22.7 26.3 N.A.
Protein Similarity: N.A. N.A. N.A. 38.1 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 7 0 69 7 7 0 19 0 13 0 69 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 13 0 63 0 0 7 0 0 7 0 63 0 0 0 % D
% Glu: 7 0 7 0 0 0 0 7 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 13 7 75 7 63 0 0 19 13 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % H
% Ile: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 0 0 0 0 0 0 0 13 0 7 0 0 0 0 % K
% Leu: 13 0 7 7 63 69 0 0 7 7 7 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 63 0 0 13 7 19 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 7 0 7 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 0 7 50 7 7 7 0 69 0 63 7 13 82 7 7 % S
% Thr: 7 7 13 0 0 7 0 7 0 0 0 7 0 63 0 % T
% Val: 0 57 0 0 0 0 0 0 0 0 0 7 0 7 0 % V
% Trp: 0 7 7 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _